3uxu

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Current revision (06:15, 17 October 2024) (edit) (undo)
 
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<StructureSection load='3uxu' size='340' side='right'caption='[[3uxu]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
<StructureSection load='3uxu' size='340' side='right'caption='[[3uxu]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3uxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ssv1 Ssv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UXU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3uxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_spindle-shaped_virus_1 Sulfolobus spindle-shaped virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UXU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.706&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">d335 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=244589 SSV1])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uxu OCA], [https://pdbe.org/3uxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uxu RCSB], [https://www.ebi.ac.uk/pdbsum/3uxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uxu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uxu OCA], [https://pdbe.org/3uxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uxu RCSB], [https://www.ebi.ac.uk/pdbsum/3uxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uxu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/INTG_SSV1 INTG_SSV1]] This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome. Essential for virus infection.
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[https://www.uniprot.org/uniprot/VINT_SSV1 VINT_SSV1] This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome. Essential for virus infection.<ref>PMID:10430570</ref> <ref>PMID:22683788</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ssv1]]
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[[Category: Sulfolobus spindle-shaped virus 1]]
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[[Category: Eilers, B J]]
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[[Category: Eilers BJ]]
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[[Category: Lawrence, C M]]
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[[Category: Lawrence CM]]
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[[Category: Young, M J]]
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[[Category: Young MJ]]
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[[Category: Archaea]]
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[[Category: Archaeal virus]]
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[[Category: Disulfide]]
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[[Category: Hyperthermophilic]]
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[[Category: Integrase]]
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[[Category: Recombination]]
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Current revision

The structure of the catalytic domain of the Sulfolobus Spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of DNA cleavage in trans

PDB ID 3uxu

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