3v94

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Current revision (10:34, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3v94' size='340' side='right'caption='[[3v94]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='3v94' size='340' side='right'caption='[[3v94]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3v94]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V94 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V94 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3v94]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V94 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V94 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=WYQ:PROPAN-2-YL+{[4-ETHOXY-3-(1-METHYL-7-OXO-3-PROPYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PHENYL]SULFONYL}CARBAMATE'>WYQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3v93|3v93]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=WYQ:PROPAN-2-YL+{[4-ETHOXY-3-(1-METHYL-7-OXO-3-PROPYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PHENYL]SULFONYL}CARBAMATE'>WYQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDEC, TcrPDEC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 TRYCR])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v94 OCA], [https://pdbe.org/3v94 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v94 RCSB], [https://www.ebi.ac.uk/pdbsum/3v94 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v94 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v94 OCA], [https://pdbe.org/3v94 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v94 RCSB], [https://www.ebi.ac.uk/pdbsum/3v94 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v94 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q53I60_TRYCR Q53I60_TRYCR]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trycr]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Chen, G]]
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[[Category: Chen G]]
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[[Category: Ke, H]]
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[[Category: Ke H]]
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[[Category: Kunz, S]]
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[[Category: Kunz S]]
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[[Category: Martinelli, S]]
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[[Category: Martinelli S]]
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[[Category: Robinson, H]]
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[[Category: Robinson H]]
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[[Category: Seebeck, T]]
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[[Category: Seebeck T]]
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[[Category: Wan, Y]]
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[[Category: Wan Y]]
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[[Category: Wang, H]]
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[[Category: Wang H]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Trypanosoma pde parasite]]
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Current revision

TcrPDEC1 catalytic domain in complex with inhibitor wyq16

PDB ID 3v94

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