7y3k
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of SALL4 ZFC4 bound with 16 bp AT-rich dsDNA== | |
| - | + | <StructureSection load='7y3k' size='340' side='right'caption='[[7y3k]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7y3k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y3K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y3k OCA], [https://pdbe.org/7y3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y3k RCSB], [https://www.ebi.ac.uk/pdbsum/7y3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y3k ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SALL4_HUMAN SALL4_HUMAN] Acro-renal-ocular syndrome;IVIC syndrome;Okihiro syndrome due to 20q13 microdeletion;Okihiro syndrome due to a point mutation. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SALL4_HUMAN SALL4_HUMAN] Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.<ref>PMID:23012367</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Ru W]] | ||
| + | [[Category: Xu C]] | ||
Revision as of 06:07, 26 October 2022
Structure of SALL4 ZFC4 bound with 16 bp AT-rich dsDNA
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