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8d9z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Cobra alpha-neurotoxin in complex with Centi-3FTX-D09 antibody== | |
| - | + | <StructureSection load='8d9z' size='340' side='right'caption='[[8d9z]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8d9z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Naja_nivea Naja nivea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D9Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d9z OCA], [https://pdbe.org/8d9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d9z RCSB], [https://www.ebi.ac.uk/pdbsum/8d9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d9z ProSAT]</span></td></tr> |
| - | [[Category: Glanville | + | </table> |
| - | [[Category: Kwong | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/3L21_NAJNI 3L21_NAJNI] Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.[UniProtKB:P60615] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Verardi | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Naja nivea]] | ||
| + | [[Category: Glanville J]] | ||
| + | [[Category: Kwong PD]] | ||
| + | [[Category: Pletnev S]] | ||
| + | [[Category: Tully ES]] | ||
| + | [[Category: Verardi R]] | ||
Current revision
Crystal structure of Cobra alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
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