7uwk
From Proteopedia
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| - | ==== | + | ==Structure of the higher-order IL-25-IL-17RB complex== | 
| - | <StructureSection load='7uwk' size='340' side='right'caption='[[7uwk]]' scene=''> | + | <StructureSection load='7uwk' size='340' side='right'caption='[[7uwk]], [[Resolution|resolution]] 4.40Å' scene=''> | 
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7uwk]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UWK FirstGlance]. <br> | 
| </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwk OCA], [https://pdbe.org/7uwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwk RCSB], [https://www.ebi.ac.uk/pdbsum/7uwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwk ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwk OCA], [https://pdbe.org/7uwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwk RCSB], [https://www.ebi.ac.uk/pdbsum/7uwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwk ProSAT]</span></td></tr> | ||
| </table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/IL25_HUMAN IL25_HUMAN]] Induces activation of NF-kappa-B and stimulates production of the pro-inflammatory chemokine IL-8. Pro-inflammatory cytokine favoring Th2-type immune responses. | ||
| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| [[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category:  | + | [[Category: Caveney NA]] | 
| + | [[Category: Garcia KC]] | ||
| + | [[Category: Jude KM]] | ||
| + | [[Category: Wilson SC]] | ||
Revision as of 16:49, 7 September 2022
Structure of the higher-order IL-25-IL-17RB complex
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