7y7y
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human GABA transporter GAT1 bound with nipecotic acid in NaCl solution in an inward-occluded state at 2.4 angstrom== | |
| - | + | <StructureSection load='7y7y' size='340' side='right'caption='[[7y7y]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7y7y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y7Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ID7:(3R)-piperidine-3-carboxylic+acid'>ID7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y7y OCA], [https://pdbe.org/7y7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y7y RCSB], [https://www.ebi.ac.uk/pdbsum/7y7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y7y ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN] Myoclonic-astatic epilepsy. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN] Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Huang J]] | ||
| + | [[Category: Kong F]] | ||
| + | [[Category: Lei J]] | ||
| + | [[Category: Tan J]] | ||
| + | [[Category: Yan C]] | ||
| + | [[Category: Yuan Y]] | ||
| + | [[Category: Zhu A]] | ||
Revision as of 16:59, 26 April 2023
Cryo-EM structure of human GABA transporter GAT1 bound with nipecotic acid in NaCl solution in an inward-occluded state at 2.4 angstrom
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Categories: Homo sapiens | Large Structures | Huang J | Kong F | Lei J | Tan J | Yan C | Yuan Y | Zhu A
