7umg
From Proteopedia
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| - | ==== | + | ==Crystal structure of human CD8aa-MR1-Ac-6-FP complex== |
| - | <StructureSection load='7umg' size='340' side='right'caption='[[7umg]]' scene=''> | + | <StructureSection load='7umg' size='340' side='right'caption='[[7umg]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7umg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UMG FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7umg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7umg OCA], [https://pdbe.org/7umg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7umg RCSB], [https://www.ebi.ac.uk/pdbsum/7umg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7umg ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=30W:N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE'>30W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7umg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7umg OCA], [https://pdbe.org/7umg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7umg RCSB], [https://www.ebi.ac.uk/pdbsum/7umg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7umg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/HMR1_HUMAN HMR1_HUMAN]] Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.<ref>PMID:12794138</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Awad W]] |
| + | [[Category: Rossjohn J]] | ||
Revision as of 16:49, 7 September 2022
Crystal structure of human CD8aa-MR1-Ac-6-FP complex
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