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3w8d

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Current revision (12:57, 8 November 2023) (edit) (undo)
 
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<StructureSection load='3w8d' size='340' side='right'caption='[[3w8d]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
<StructureSection load='3w8d' size='340' side='right'caption='[[3w8d]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3w8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcfa Alcfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W8D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3w8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W8D FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DXX:METHYLMALONIC+ACID'>DXX</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3w8e|3w8e]], [[3w8f|3w8f]], [[3vdr|3vdr]], [[2yz7|2yz7]], [[3vdq|3vdq]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DXX:METHYLMALONIC+ACID'>DXX</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-hydroxybutyrate_dehydrogenase 3-hydroxybutyrate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.30 1.1.1.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w8d OCA], [https://pdbe.org/3w8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w8d RCSB], [https://www.ebi.ac.uk/pdbsum/3w8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w8d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w8d OCA], [https://pdbe.org/3w8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w8d RCSB], [https://www.ebi.ac.uk/pdbsum/3w8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w8d ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0VWQ0_ALCFA D0VWQ0_ALCFA]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-hydroxybutyrate dehydrogenase]]
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[[Category: Alcaligenes faecalis]]
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[[Category: Alcfa]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hoque, M M]]
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[[Category: Hoque MM]]
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[[Category: Kanazawa, H]]
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[[Category: Kanazawa H]]
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[[Category: Suzuki, K]]
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[[Category: Suzuki K]]
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[[Category: Takenaka, A]]
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[[Category: Takenaka A]]
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[[Category: Tsunoda, M]]
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[[Category: Tsunoda M]]
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[[Category: Yamamoto, T]]
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[[Category: Yamamoto T]]
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[[Category: Mitochondria]]
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[[Category: Nad+ binding methylmalonate binding]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Oxidreductase]]
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[[Category: Rossmann fold]]
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Current revision

Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate

PDB ID 3w8d

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