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3wcz
From Proteopedia
(Difference between revisions)
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<StructureSection load='3wcz' size='340' side='right'caption='[[3wcz]], [[Resolution|resolution]] 1.30Å' scene=''> | <StructureSection load='3wcz' size='340' side='right'caption='[[3wcz]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3wcz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3wcz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WCZ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcz OCA], [https://pdbe.org/3wcz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wcz RCSB], [https://www.ebi.ac.uk/pdbsum/3wcz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcz OCA], [https://pdbe.org/3wcz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wcz RCSB], [https://www.ebi.ac.uk/pdbsum/3wcz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AK2E4_BOMMO AK2E4_BOMMO] NADP-dependent oxidoreductase with high 3-dehydroecdysone reductase activity. May play a role in the regulation of molting. Has lower activity with phenylglyoxal and isatin (in vitro). Has no activity with NADH as cosubstrate. Has no activity with nitrobenzaldehyde and 3-hydroxybenzaldehyde.<ref>PMID:24012638</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bombyx mori]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Wilson | + | [[Category: Wilson DK]] |
| - | [[Category: Yamamoto | + | [[Category: Yamamoto K]] |
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Current revision
Crystal structure of Bombyx mori aldo-keto reductase (AKR2E4) in complex with NADP
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