We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
3zh3
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3zh3' size='340' side='right'caption='[[3zh3]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='3zh3' size='340' side='right'caption='[[3zh3]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3zh3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3zh3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_D39 Streptococcus pneumoniae D39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZH3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZH3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zh3 OCA], [https://pdbe.org/3zh3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zh3 RCSB], [https://www.ebi.ac.uk/pdbsum/3zh3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zh3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zh3 OCA], [https://pdbe.org/3zh3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zh3 RCSB], [https://www.ebi.ac.uk/pdbsum/3zh3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zh3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/MURA1_STRP2 MURA1_STRP2] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity). Target for the antibiotic fosfomycin. Involved in heteroresistance to antibiotic fosfomycin. Heteroresistance is the ability of a clonal population to grow one or several subpopulations at a frequency of 10(-7) to 10(-3) in the presence of a higher antibiotic concentration than that predicted to be effective by measurement of the minimum inhibitory concentration (MIC) (PubMed:23571543).[HAMAP-Rule:MF_00111]<ref>PMID:23571543</ref> | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 26: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Streptococcus pneumoniae D39]] |
| - | + | [[Category: Gutierrez-Fernandez J]] | |
| - | [[Category: Gutierrez-Fernandez | + | [[Category: Hermoso JA]] |
| - | [[Category: Hermoso | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
crystal structure of S. pneumoniae D39 native MurA1
| |||||||||||
