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7yxa

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Revision as of 12:54, 22 February 2023

XFEL crystal structure of the human sphingosine 1 phosphate receptor 5 in complex with ONO-5430608

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OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7yxa"

@@ Line 3: / Line 3: @@
 <StructureSection load='7yxa' size='340' side='right'caption='[[7yxa]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[7yxa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YXA FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7yxa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YXA FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B2O:4-[6-(2-naphthalen-1-ylethoxy)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-ium-3-yl]butanoic+acid'>B2O</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yxa OCA], [https://pdbe.org/7yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yxa RCSB], [https://www.ebi.ac.uk/pdbsum/7yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yxa ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/S1PR5_HUMAN S1PR5_HUMAN]] Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
+[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/S1PR5_HUMAN S1PR5_HUMAN] Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Borshchevskiy, V]]
+[[Category: Borshchevskiy V]]
-[[Category: Bourenkov, G]]
+[[Category: Bourenkov G]]
-[[Category: Bukhdruker, S]]
+[[Category: Bukhdruker S]]
-[[Category: Cherezov, V]]
+[[Category: Cherezov V]]
-[[Category: Cho, Y]]
+[[Category: Cho Y]]
-[[Category: Ergasheva, M]]
+[[Category: Ergasheva M]]
-[[Category: Gerasimov, A]]
+[[Category: Gerasimov A]]
-[[Category: Gordeliy, V]]
+[[Category: Gordeliy V]]
-[[Category: Gusach, A]]
+[[Category: Gusach A]]
-[[Category: Gushchin, I]]
+[[Category: Gushchin I]]
-[[Category: Hu, H]]
+[[Category: Hu H]]
-[[Category: Huyn, H J]]
+[[Category: Huyn HJ]]
-[[Category: Khorn, P]]
+[[Category: Khorn P]]
-[[Category: Khusainov, G]]
+[[Category: Khusainov G]]
-[[Category: Kovalev, K]]
+[[Category: Kovalev K]]
-[[Category: Kovaleva, M]]
+[[Category: Kovaleva M]]
-[[Category: Liu, W]]
+[[Category: Liu W]]
-[[Category: Luginina, A]]
+[[Category: Luginina A]]
-[[Category: Lyapina, E]]
+[[Category: Lyapina E]]
-[[Category: Marin, E]]
+[[Category: Marin E]]
-[[Category: Mishin, A]]
+[[Category: Mishin A]]
-[[Category: Okhrimenko, I]]
+[[Category: Okhrimenko I]]
-[[Category: Orekhov, P]]
+[[Category: Orekhov P]]
-[[Category: Park, G]]
+[[Category: Park G]]
-[[Category: Park, J]]
+[[Category: Park J]]
-[[Category: Park, S]]
+[[Category: Park S]]
-[[Category: Popov, P]]
+[[Category: Popov P]]
-[[Category: Rogachev, A]]
+[[Category: Rogachev A]]
-[[Category: Shevtsov, M]]
+[[Category: Shevtsov M]]
-[[Category: Vakhrameev, D]]
+[[Category: Vakhrameev D]]
-[[Category: Weierstall, U]]
+[[Category: Weierstall U]]
-[[Category: G-protein coupled receptor]]
-[[Category: Gpcr]]
-[[Category: Membrane protein]]
-[[Category: S1p5]]
-[[Category: Serial femtosecond crystallography]]
-[[Category: Sfx]]
-[[Category: Sphingosine-1-phosphate]]
-[[Category: Sphingosine-1-phosphate receptor]]
-[[Category: X-ray free electron laser]]
-[[Category: Xfel]]

7yxa

From Proteopedia

Revision as of 12:54, 22 February 2023

XFEL crystal structure of the human sphingosine 1 phosphate receptor 5 in complex with ONO-5430608

Structural highlights

Function

Contents

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