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3zv0

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Current revision (10:43, 9 May 2024) (edit) (undo)
 
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<StructureSection load='3zv0' size='340' side='right'caption='[[3zv0]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='3zv0' size='340' side='right'caption='[[3zv0]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zv0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZV0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zv0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZV0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zuz|3zuz]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zv0 OCA], [https://pdbe.org/3zv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zv0 RCSB], [https://www.ebi.ac.uk/pdbsum/3zv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zv0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zv0 OCA], [https://pdbe.org/3zv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zv0 RCSB], [https://www.ebi.ac.uk/pdbsum/3zv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zv0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SHQ1_YEAST SHQ1_YEAST]] Involved in the early biogenesis steps of box H/ACA snoRNP assembly.<ref>PMID:12228251</ref> [[https://www.uniprot.org/uniprot/CBF5_YEAST CBF5_YEAST]] Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. May function as a pseudouridine synthase. Binds in vitro to centromeres and microtubules. It is a centromeric DNA-CBF3-binding factor which is involved in mitotic chromosome segregation. Essential for cell growth.<ref>PMID:8336724</ref> <ref>PMID:9315678</ref> <ref>PMID:9472021</ref> <ref>PMID:9848653</ref> <ref>PMID:10523634</ref>
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[https://www.uniprot.org/uniprot/SHQ1_YEAST SHQ1_YEAST] Involved in the early biogenesis steps of box H/ACA snoRNP assembly.<ref>PMID:12228251</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Blaud, M]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Godin, K]]
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[[Category: Blaud M]]
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[[Category: Grozdanov, P N]]
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[[Category: Godin K]]
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[[Category: Leulliot, N]]
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[[Category: Grozdanov PN]]
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[[Category: Liger, D]]
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[[Category: Leulliot N]]
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[[Category: Machado-Pinilla, R]]
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[[Category: Liger D]]
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[[Category: Meier, U T]]
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[[Category: Machado-Pinilla R]]
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[[Category: Rety, S]]
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[[Category: Meier UT]]
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[[Category: Varani, G]]
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[[Category: Rety S]]
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[[Category: Walbott, H]]
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[[Category: Varani G]]
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[[Category: VanTilbeurgh, H]]
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[[Category: Walbott H]]
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[[Category: Cell cycle]]
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[[Category: VanTilbeurgh H]]
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[[Category: Rnp assembly]]
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[[Category: Telomerase]]
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[[Category: X-linked dyskeratosis congenita]]
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Current revision

Structure of the SHQ1P-CBF5P complex

PDB ID 3zv0

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Proteopedia Page Contributors and Editors (what is this?)

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