3zyi

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Current revision (11:16, 20 December 2023) (edit) (undo)
 
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<StructureSection load='3zyi' size='340' side='right'caption='[[3zyi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3zyi' size='340' side='right'caption='[[3zyi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zyg|3zyg]], [[2dl9|2dl9]], [[3zyj|3zyj]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyi OCA], [https://pdbe.org/3zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyi RCSB], [https://www.ebi.ac.uk/pdbsum/3zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyi OCA], [https://pdbe.org/3zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyi RCSB], [https://www.ebi.ac.uk/pdbsum/3zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LRRC4_HUMAN LRRC4_HUMAN]] Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). [[https://www.uniprot.org/uniprot/NTNG2_HUMAN NTNG2_HUMAN]] Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.<ref>PMID:21946559</ref>
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[https://www.uniprot.org/uniprot/LRRC4_HUMAN LRRC4_HUMAN] Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aricescu, A R]]
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[[Category: Aricescu AR]]
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[[Category: Coles, C H]]
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[[Category: Coles CH]]
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[[Category: Harlos, K]]
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[[Category: Harlos K]]
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[[Category: Jones, E Y]]
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[[Category: Jones EY]]
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[[Category: McIlhinney, R A.J]]
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[[Category: McIlhinney RAJ]]
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[[Category: Perestenko, P V]]
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[[Category: Perestenko PV]]
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[[Category: Seiradake, E]]
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[[Category: Seiradake E]]
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[[Category: Cell adhesion]]
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[[Category: Lrrc4 complex]]
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[[Category: Synapse]]
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Current revision

NetrinG2 in complex with NGL2

PDB ID 3zyi

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OCA

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