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4a6s

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Current revision (11:20, 20 December 2023) (edit) (undo)
 
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<StructureSection load='4a6s' size='340' side='right'caption='[[4a6s]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='4a6s' size='340' side='right'caption='[[4a6s]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4a6s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A6S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4a6s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A6S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GS9:NAPHTHALEN-2-YL+1-THIO-BETA-D-GALACTOPYRANOSIDE'>GS9</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1uoj|1uoj]], [[1l7l|1l7l]], [[2vxj|2vxj]], [[1oko|1oko]], [[3zyh|3zyh]], [[2wyf|2wyf]], [[3zyb|3zyb]], [[3zyf|3zyf]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GS9:NAPHTHALEN-2-YL+1-THIO-BETA-D-GALACTOPYRANOSIDE'>GS9</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a6s OCA], [https://pdbe.org/4a6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a6s RCSB], [https://www.ebi.ac.uk/pdbsum/4a6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a6s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a6s OCA], [https://pdbe.org/4a6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a6s RCSB], [https://www.ebi.ac.uk/pdbsum/4a6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a6s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE]] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
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[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Blanchard, B]]
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[[Category: Blanchard B]]
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[[Category: Chiao, T S]]
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[[Category: Chiao TS]]
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[[Category: Ganne, G]]
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[[Category: Ganne G]]
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[[Category: Giguere, D]]
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[[Category: Giguere D]]
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[[Category: Imberty, A]]
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[[Category: Imberty A]]
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[[Category: Rodrigue, J]]
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[[Category: Rodrigue J]]
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[[Category: Roy, R]]
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[[Category: Roy R]]
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[[Category: Saucier, C]]
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[[Category: Saucier C]]
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[[Category: Varrot, A]]
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[[Category: Varrot A]]
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[[Category: Glycomimetic]]
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[[Category: Sugar binding protein]]
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[[Category: Sugar-binding protein]]
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Current revision

Structure of the PAIL lectin from Pseudomonas aeruginosa in complex with 2-Naphtyl-1-thio-beta-D-galactopyranoside

PDB ID 4a6s

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