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4aq7

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Current revision (11:32, 20 December 2023) (edit) (undo)
 
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<StructureSection load='4aq7' size='340' side='right'caption='[[4aq7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4aq7' size='340' side='right'caption='[[4aq7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4aq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AQ7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4aq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AQ7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=LMS:[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL+SULFAMATE'>LMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ajg|2ajg]], [[2ajh|2ajh]], [[2aji|2aji]], [[4arc|4arc]], [[4ari|4ari]], [[4as1|4as1]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=LMS:[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL+SULFAMATE'>LMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Leucine--tRNA_ligase Leucine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.4 6.1.1.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq7 OCA], [https://pdbe.org/4aq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aq7 RCSB], [https://www.ebi.ac.uk/pdbsum/4aq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aq7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq7 OCA], [https://pdbe.org/4aq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aq7 RCSB], [https://www.ebi.ac.uk/pdbsum/4aq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aq7 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYL_ECOLI SYL_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Leucine--tRNA ligase]]
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[[Category: Crepin T]]
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[[Category: Crepin, T]]
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[[Category: Cusack S]]
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[[Category: Cusack, S]]
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[[Category: Lincecum Jr TL]]
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[[Category: Jr, T L.Lincecum]]
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[[Category: Martinis SA]]
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[[Category: Martinis, S A]]
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[[Category: Palencia A]]
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[[Category: Palencia, A]]
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[[Category: Vu MT]]
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[[Category: Vu, M T]]
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[[Category: Atp-binding]]
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[[Category: Class i aminoacyl-trna synthetase]]
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[[Category: Ligase]]
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[[Category: Ligase-rna complex]]
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[[Category: Metal-binding]]
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[[Category: Protein biosynthesis]]
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Current revision

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

PDB ID 4aq7

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