7zjx

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'''Unreleased structure'''
 
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The entry 7zjx is ON HOLD until Paper Publication
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==Rabbit 80S ribosome programmed with SECIS and SBP2==
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<StructureSection load='7zjx' size='340' side='right'caption='[[7zjx]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors: Hilal, T., Simonovic, M., Spahn, C.M.T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7zjx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricket_paralysis_virus Cricket paralysis virus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZJX FirstGlance]. <br>
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Description: Rabbit 80S ribosome programmed with SECIS and SBP2
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=4AC:N(4)-ACETYLCYTIDINE-5-MONOPHOSPHATE'>4AC</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=6MZ:N6-METHYLADENOSINE-5-MONOPHOSPHATE'>6MZ</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=AAC:ACETYLAMINO-ACETIC+ACID'>AAC</scene>, <scene name='pdbligand=AME:N-ACETYLMETHIONINE'>AME</scene>, <scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=HY3:3-HYDROXYPROLINE'>HY3</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MA6:6N-DIMETHYLADENOSINE-5-MONOPHOSHATE'>MA6</scene>, <scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene>, <scene name='pdbligand=NMM:(2S)-2-AMINO-5-[(N-METHYLCARBAMIMIDOYL)AMINO]PENTANOIC+ACID'>NMM</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SAC:N-ACETYL-SERINE'>SAC</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zjx OCA], [https://pdbe.org/7zjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zjx RCSB], [https://www.ebi.ac.uk/pdbsum/7zjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zjx ProSAT]</span></td></tr>
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[[Category: Simonovic, M]]
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</table>
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[[Category: Hilal, T]]
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== Disease ==
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[[Category: Spahn, C.M.T]]
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[[https://www.uniprot.org/uniprot/SEBP2_HUMAN SEBP2_HUMAN]] Short stature-delayed bone age due to thyroid hormone metabolism deficiency. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[[https://www.uniprot.org/uniprot/SEBP2_HUMAN SEBP2_HUMAN]] Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
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__TOC__
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</StructureSection>
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[[Category: Cricket paralysis virus]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Oryctolagus cuniculus]]
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[[Category: Hilal T]]
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[[Category: Simonovic M]]
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[[Category: Spahn CMT]]

Revision as of 16:41, 7 September 2022

Rabbit 80S ribosome programmed with SECIS and SBP2

PDB ID 7zjx

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