7qqg
From Proteopedia
(Difference between revisions)
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==Crystal structure of MYORG bound to 1-deoxygalactonojirimycin== | ==Crystal structure of MYORG bound to 1-deoxygalactonojirimycin== | ||
- | <StructureSection load='7qqg' size='340' side='right'caption='[[7qqg]]' scene=''> | + | <StructureSection load='7qqg' size='340' side='right'caption='[[7qqg]], [[Resolution|resolution]] 2.43Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QQG FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7qqg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QQG FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qqg OCA], [https://pdbe.org/7qqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qqg RCSB], [https://www.ebi.ac.uk/pdbsum/7qqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qqg ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGJ:(2R,3S,4R,5S)-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL'>DGJ</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qqg OCA], [https://pdbe.org/7qqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qqg RCSB], [https://www.ebi.ac.uk/pdbsum/7qqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qqg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Disease == | ||
+ | [[https://www.uniprot.org/uniprot/MYORG_HUMAN MYORG_HUMAN]] Bilateral striopallidodentate calcinosis. The disease is caused by variants affecting the gene represented in this entry. | ||
+ | == Function == | ||
+ | [[https://www.uniprot.org/uniprot/MYORG_HUMAN MYORG_HUMAN]] Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2.[UniProtKB:Q69ZQ1] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Davies GJ]] | [[Category: Davies GJ]] | ||
[[Category: Meek RW]] | [[Category: Meek RW]] |
Revision as of 19:23, 7 September 2022
Crystal structure of MYORG bound to 1-deoxygalactonojirimycin
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