This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8dqz
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction== | ==Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction== | ||
| - | <StructureSection load='8dqz' size='340' side='right'caption='[[8dqz]]' scene=''> | + | <StructureSection load='8dqz' size='340' side='right'caption='[[8dqz]], [[Resolution|resolution]] 2.92Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DQZ FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[8dqz]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DQZ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dqz OCA], [https://pdbe.org/8dqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dqz RCSB], [https://www.ebi.ac.uk/pdbsum/8dqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dqz ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.92Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dqz OCA], [https://pdbe.org/8dqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dqz RCSB], [https://www.ebi.ac.uk/pdbsum/8dqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dqz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RFC1_YEAST RFC1_YEAST] Component of the ATP-dependent clamp loader RFC complex for the POL30/PCNA homotrimer DNA clamp. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Replication factor C (RFC or activator 1) complex acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Hite RK]] | [[Category: Hite RK]] | ||
[[Category: Schrecker M]] | [[Category: Schrecker M]] | ||
Current revision
Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction
| |||||||||||
