This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3whn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Hemerythrin-like domain of DcrH I119H mutant (met)== | ==Hemerythrin-like domain of DcrH I119H mutant (met)== | ||
| - | <StructureSection load='3whn' size='340' side='right'caption='[[3whn]]' scene=''> | + | <StructureSection load='3whn' size='340' side='right'caption='[[3whn]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WHN FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[3whn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._Hildenborough Desulfovibrio vulgaris str. Hildenborough]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WHN FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3whn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3whn OCA], [https://pdbe.org/3whn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3whn RCSB], [https://www.ebi.ac.uk/pdbsum/3whn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3whn ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CFO:CHLORO+DIIRON-OXO+MOIETY'>CFO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3whn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3whn OCA], [https://pdbe.org/3whn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3whn RCSB], [https://www.ebi.ac.uk/pdbsum/3whn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3whn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q726F3_DESVH Q726F3_DESVH] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The O2-binding carboxylate-bridged diiron site in DcrH-Hr was engineered in an effort to perform the H2O2-dependent oxidation of external substrates. A His residue was introduced near the diiron site in place of a conserved residue, Ile119. The I119H variant promotes the oxidation of guaiacol and 1,4-cyclohexadiene upon addition of H2O2. | ||
| + | |||
| + | HO-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin.,Okamoto Y, Onoda A, Sugimoto H, Takano Y, Hirota S, Kurtz DM, Shiro Y, Hayashi T Chem Commun (Camb). 2014 Jan 8. PMID:24400317<ref>PMID:24400317</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 3whn" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Desulfovibrio vulgaris str. Hildenborough]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hayashi T]] | [[Category: Hayashi T]] | ||
Current revision
Hemerythrin-like domain of DcrH I119H mutant (met)
| |||||||||||
