This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7tmq
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==V1 complex lacking subunit C from Saccharomyces cerevisiae, State 3== | ==V1 complex lacking subunit C from Saccharomyces cerevisiae, State 3== | ||
| - | <StructureSection load='7tmq' size='340' side='right'caption='[[7tmq]]' scene=''> | + | <StructureSection load='7tmq' size='340' side='right'caption='[[7tmq]], [[Resolution|resolution]] 3.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TMQ FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7tmq]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TMQ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tmq OCA], [https://pdbe.org/7tmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tmq RCSB], [https://www.ebi.ac.uk/pdbsum/7tmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tmq ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tmq OCA], [https://pdbe.org/7tmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tmq RCSB], [https://www.ebi.ac.uk/pdbsum/7tmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tmq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VATA_YEAST VATA_YEAST] Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase (vacuolar ATPase) is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mV, inside positive and acidic, in the vacuolar membrane vesicles. It may participate in maintenance of cytoplasmic Ca(2+) homeostasis. This is a catalytic subunit.<ref>PMID:1534148</ref> PI-SceI is an endonuclease that can cleave at a site present in a VMA1 allele that lacks the derived endonuclease segment of the open reading frame; cleavage at this site only occurs during meiosis and initiates "homing", a genetic event that converts a VMA1 allele lacking VDE into one that contains it.<ref>PMID:1534148</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[ATPase 3D structures|ATPase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Bueler SA]] | [[Category: Bueler SA]] | ||
[[Category: Jaskolka MC]] | [[Category: Jaskolka MC]] | ||
Current revision
V1 complex lacking subunit C from Saccharomyces cerevisiae, State 3
| |||||||||||
