7vig

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'''Unreleased structure'''
 
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The entry 7vig is ON HOLD until Paper Publication
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==Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CBP-307==
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<StructureSection load='7vig' size='340' side='right'caption='[[7vig]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7vig]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VIG FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7I4:1-[[2-fluoranyl-4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic+acid'>7I4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vig OCA], [https://pdbe.org/7vig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vig RCSB], [https://www.ebi.ac.uk/pdbsum/7vig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vig ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Gan B]]
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[[Category: Ren RB]]
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[[Category: Xiao QJ]]
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[[Category: Yu LY]]

Revision as of 06:18, 28 September 2022

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CBP-307

PDB ID 7vig

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