1ice

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ice.jpg|left|200px]]
+
[[Image:1ice.png|left|200px]]
<!--
<!--
Line 12: Line 12:
-
==Overview==
+
{{ABSTRACT_8035875}}
-
Interleukin-1 beta converting enzyme (ICE) processes an inactive precursor to the proinflammatory cytokine, interleukin-1 beta, and may regulate programmed cell death in neuronal cells. The high-resolution structure of human ICE in complex with an inhibitor has been determined by X-ray diffraction. The structure confirms the relationship between human ICE and cell-death proteins in other organisms. The active site spans both the 10 and 20K subunits, which associate to form a tetramer, suggesting a mechanism for ICE autoactivation.
+
==About this Structure==
==About this Structure==
1ICE is a [[Single protein]] structure. The following page contains interesting information on the relation of 1ICE with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb56_1.html Caspases]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ICE OCA].
1ICE is a [[Single protein]] structure. The following page contains interesting information on the relation of 1ICE with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb56_1.html Caspases]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ICE OCA].
- 
-
==Reference==
 
-
Structure and mechanism of interleukin-1 beta converting enzyme., Wilson KP, Black JA, Thomson JA, Kim EE, Griffith JP, Navia MA, Murcko MA, Chambers SP, Aldape RA, Raybuck SA, et al., Nature. 1994 Jul 28;370(6487):270-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8035875 8035875]
 
[[Category: Caspase-1]]
[[Category: Caspase-1]]
[[Category: Caspases]]
[[Category: Caspases]]
Line 28: Line 24:
[[Category: Wilson, K P.]]
[[Category: Wilson, K P.]]
[[Category: Cytokine]]
[[Category: Cytokine]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:50:26 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:32:22 2008''

Revision as of 14:32, 26 June 2008

Image:1ice.png

Template:STRUCTURE 1ice

STRUCTURE AND MECHANISM OF INTERLEUKIN-1BETA CONVERTING ENZYME


Template:ABSTRACT 8035875

About this Structure

1ICE is a Single protein structure. The following page contains interesting information on the relation of 1ICE with [Caspases]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:32:22 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ice"
Personal tools