4cyg

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Current revision (12:17, 20 December 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cyg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CYG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cyg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CYG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=RRV:(2R)-2,4-DIHYDROXY-N-[(3S)-3-HYDROXY-4-PHENYLBUTYL]-3,3-DIMETHYLBUTANAMIDE'>RRV</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=RRV:(2R)-2,4-DIHYDROXY-N-[(3S)-3-HYDROXY-4-PHENYLBUTYL]-3,3-DIMETHYLBUTANAMIDE'>RRV</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cyg OCA], [https://pdbe.org/4cyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cyg RCSB], [https://www.ebi.ac.uk/pdbsum/4cyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cyg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cyg OCA], [https://pdbe.org/4cyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cyg RCSB], [https://www.ebi.ac.uk/pdbsum/4cyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cyg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VNN1_HUMAN VNN1_HUMAN]] Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.<ref>PMID:10567687</ref> <ref>PMID:11491533</ref>
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[https://www.uniprot.org/uniprot/VNN1_HUMAN VNN1_HUMAN] Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.<ref>PMID:10567687</ref> <ref>PMID:11491533</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Current revision

The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation

PDB ID 4cyg

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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