This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ih5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ih5.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1ih5.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ih5| PDB=1ih5 | SCENE= }}
{{STRUCTURE_1ih5| PDB=1ih5 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF AQUAPORIN-1'''
+
===CRYSTAL STRUCTURE OF AQUAPORIN-1===
-
==Overview==
+
<!--
-
The water-selective pathway through the aquaporin-1 membrane channel has been visualized by fitting an atomic model to a 3.7-A resolution three-dimensional density map. This map was determined by analyzing images and electron diffraction patterns of lipid-reconstituted two-dimensional crystals of aquaporin-1 preserved in vitrified buffer in the absence of any additive. The aqueous pathway is characterized by a size-selective pore that is approximately 4.0 +/- 0.5A in diameter, spans a length of approximately 18A, and bends by approximately 25 degrees as it traverses the bilayer. This narrow pore is connected by wide, funnel-shaped openings at the extracellular and cytoplasmic faces. The size-selective pore is outlined mostly by hydrophobic residues, resulting in a relatively inert pathway conducive to diffusion-limited water flow. The apex of the curved pore is close to the locations of the in-plane pseudo-2-fold symmetry axis that relates the N- and C-terminal halves and the conserved, functionally important N76 and N192 residues.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11171962}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11171962 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11171962}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Two-dimensional crystal]]
[[Category: Two-dimensional crystal]]
[[Category: Water channel]]
[[Category: Water channel]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:59:38 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 12:10:15 2008''

Revision as of 09:10, 1 July 2008

Image:1ih5.png

Template:STRUCTURE 1ih5

CRYSTAL STRUCTURE OF AQUAPORIN-1

Template:ABSTRACT PUBMED 11171962

About this Structure

1IH5 is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1hw0. Full crystallographic information is available from OCA.

Reference

Visualization of a water-selective pore by electron crystallography in vitreous ice., Ren G, Reddy VS, Cheng A, Melnyk P, Mitra AK, Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1398-403. Epub 2001 Jan 30. PMID:11171962

Page seeded by OCA on Tue Jul 1 12:10:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ih5"
Personal tools