1iiu

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[[Image:1iiu.jpg|left|200px]]
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{{STRUCTURE_1iiu| PDB=1iiu | SCENE= }}
{{STRUCTURE_1iiu| PDB=1iiu | SCENE= }}
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'''Chicken plasma retinol-binding protein (RBP)'''
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===Chicken plasma retinol-binding protein (RBP)===
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==Overview==
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The crystal structure of the specific carrier of retinol (retinol-binding protein, RBP) purified from chicken plasma has been determined (space group P2(1)2(1)2(1), with a=46.06(5) A, b=53.56(6) A, c=73.41(8) A, and one protein molecule in the asymmetric unit). Despite being obtained from a species phylogenetically distant from mammals, chicken holoRBP has an overall structure that closely resembles the previously determined structures of mammalian holoRBPs. The lack in chicken RBP of eight carboxy-terminal amino acid residues characteristic of mammalian RBPs does not significantly affect the protein structure. A distinctive feature of the avian protein is a better definition of the loop 63-67, close to the opening of the beta-barrel cavity accommodating the retinol molecule, which is rather disordered in the structures of mammalian RBPs.
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(as it appears on PubMed at http://www.pubmed.gov), where 11738088 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11738088}}
==About this Structure==
==About this Structure==
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[[Category: Rbp]]
[[Category: Rbp]]
[[Category: Retinol]]
[[Category: Retinol]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:03:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 12:17:35 2008''

Revision as of 09:17, 1 July 2008

Template:STRUCTURE 1iiu

Chicken plasma retinol-binding protein (RBP)

Template:ABSTRACT PUBMED 11738088

About this Structure

1IIU is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:11738088

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