1in0

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{{STRUCTURE_1in0| PDB=1in0 | SCENE= }}
{{STRUCTURE_1in0| PDB=1in0 | SCENE= }}
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'''YAJQ PROTEIN (HI1034)'''
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===YAJQ PROTEIN (HI1034)===
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==Overview==
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A hypothetical protein encoded by the gene YajQ of Haemophilus influenzae was selected, as part of a structural genomics project, for X-ray crystallographic structure determination and analysis to assist with the functional assignment. The protein is present in most bacteria, but not in archaea or eukaryotes. The amino acid sequence has no homology to that of other proteins. The YajQ protein was cloned, expressed, and the crystal structure determined at 2.1-A resolution by applying the multiwavelength anomalous dispersion method to a mercury derivative. The polypeptide chain is folded into two domains with identical folding topology. Each domain has a four-stranded antiparallel beta-sheet flanked on one side by two alpha-helices. This structural motif is a characteristic feature of many RNA-binding proteins. The tetrameric structure observed in the crystal suggests a possibility of binding two stretches of double-stranded nucleic acid.
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(as it appears on PubMed at http://www.pubmed.gov), where 12943362 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12943362}}
==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structure 2 function project]]
[[Category: Structure 2 function project]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 13:34:50 2008''

Revision as of 10:34, 1 July 2008

Image:1in0.png

Template:STRUCTURE 1in0

YAJQ PROTEIN (HI1034)

Template:ABSTRACT PUBMED 12943362

About this Structure

1IN0 is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains., Teplyakov A, Obmolova G, Bir N, Reddy P, Howard AJ, Gilliland GL, J Struct Funct Genomics. 2003;4(1):1-9. PMID:12943362

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