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8e22

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'''Unreleased structure'''
 
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The entry 8e22 is ON HOLD until Paper Publication
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==VPS37A_21-148==
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<StructureSection load='8e22' size='340' side='right'caption='[[8e22]]' scene=''>
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Authors: Tian, F., Ye, Y.S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8e22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E22 FirstGlance]. <br>
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Description: VPS37A_21-148
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e22 OCA], [https://pdbe.org/8e22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e22 RCSB], [https://www.ebi.ac.uk/pdbsum/8e22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e22 ProSAT]</span></td></tr>
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[[Category: Ye, Y.S]]
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</table>
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[[Category: Tian, F]]
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== Disease ==
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[https://www.uniprot.org/uniprot/VP37A_HUMAN VP37A_HUMAN] Autosomal recessive spastic paraplegia type 53. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/VP37A_HUMAN VP37A_HUMAN] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.<ref>PMID:15240819</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Tian F]]
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[[Category: Ye YS]]

Revision as of 05:26, 9 August 2023

VPS37A_21-148

PDB ID 8e22

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