8erl
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM Structure of Lipoprotein Lipase Dimer== | |
| - | + | <StructureSection load='8erl' size='340' side='right'caption='[[8erl]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8erl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ERL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ERL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8erl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8erl OCA], [https://pdbe.org/8erl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8erl RCSB], [https://www.ebi.ac.uk/pdbsum/8erl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8erl ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIPL_BOVIN LIPL_BOVIN] Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed:9188470).[UniProtKB:P06858]<ref>PMID:9188470</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gunn KH]] | ||
| + | [[Category: Neher SB]] | ||
Revision as of 07:31, 3 May 2023
CryoEM Structure of Lipoprotein Lipase Dimer
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