Sandbox Reserved 1730

From Proteopedia

(Difference between revisions)

Revision as of 19:36, 9 November 2022

This Sandbox is Reserved from August 30, 2022 through May 31, 2023 for use in the course Biochemistry I taught by Kimberly Lane at the Radford University, Radford, VA, USA. This reservation includes Sandbox Reserved 1730 through Sandbox Reserved 1749.

To get started:

Click the edit this page tab at the top. Click on Show preview and then Save the page after each step, then edit it again.
show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

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This is a default text for your page '. Click above on edit this page' to modify. Be careful with the < and > signs.

You may include any references to papers as in: the use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Function

Lysozyme binds to the membrane of bacterial cells and catalyzes the breakdown of those membranes killing the cell. The carbohydrates forming the membranes of the bacteria cells are what keep the cell together and functioning. When lysozyme binds to these membranes it catalyzes the reaction between the membrane and water, breaking the bonds between the carbohydrates and causing the membrane to fall apart. The positive charge of lysozyme is what draws it to the negative charge of the bacterial membrane.

Relevance

Lysozyme (muramidase) is an enzyme that can be found in many biological settings. The enzyme is located in saliva, tears, mucous, and human milk. Lysozyme is also found in large concentrations in egg whites from hens. Lysozyme is stable in typical conditions, thus there is a lot of research and information behind the function and structure of the enzyme.

Lysozyme serves a crucial role in our immune system due to its anti-bacterial properties. The enzyme breaks down the cell membranes of bacterial cells. Lysozyme in a single chain alkaline protein with 129 amino acid residues and four disulfide bonds. It catalyzes the breakdown of β-1,4-glycosidic bonds in the cell membrane of bacterial cells. Lysozyme is also known to have antiviral, antitumor, and anti-inflammatory properties.

Structural highlights

Lysozyme is an enzyme with 129 amino acids and four disulfide bridges. The structure of Lysozyme has two major motifs, those being alpha helices and beta strands. Lysozyme had a total of four alpha helices and five beta strands. These two motifs are regularly found in different innate immune system responses. The helices are connected with a loop, with either 2 or 3 beta strands attached to them.

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

References

↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

Retrieved from "http://52.214.119.220/wiki/index.php/Sandbox_Reserved_1730"

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 == Structural highlights ==
-Lysozyme is an enzyme with 129 amino acids and four disulfide bridges. The structure of Lysozyme has two major motifs, those being alpha helices and beta strands. Lysozyme had a total of four alpha helices and five beta strands. These two motifs are regularly found in different innate immune system responses. The helices are connected with a loop, with either 2 or 3 beta strands attached to them.
+Lysozyme is an enzyme with 129 amino acids and four disulfide bridges. The structure of Lysozyme has two major motifs, those being alpha helices and beta strands. Lysozyme had a total of four alpha helices and five beta strands. These two motifs are regularly found in different innate immune system responses. The helices are connected with a loop, with either 2 or 3 beta strands attached to them. <Structure load='1rex' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />
 This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Sandbox Reserved 1730

From Proteopedia

Revision as of 19:36, 9 November 2022

Your Heading Here (maybe something like 'Structure')

Function

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Structural highlights

References

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