8b9f

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'''Unreleased structure'''
 
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The entry 8b9f is ON HOLD
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==Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion==
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<StructureSection load='8b9f' size='340' side='right'caption='[[8b9f]], [[Resolution|resolution]] 3.93&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8b9f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E11 Echovirus E11] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B9F FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b9f OCA], [https://pdbe.org/8b9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b9f RCSB], [https://www.ebi.ac.uk/pdbsum/8b9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b9f ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Echovirus E11]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Qin L]]
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[[Category: Ren J]]
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[[Category: Stuart DI]]
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[[Category: Zhou D]]

Revision as of 08:18, 7 December 2022

Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion

PDB ID 8b9f

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