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8exf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human FAM46A-BCCIPa complex at 3.2 angstrom resolution== | |
| - | + | <StructureSection load='8exf' size='340' side='right'caption='[[8exf]], [[Resolution|resolution]] 3.22Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8exf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EXF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8exf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8exf OCA], [https://pdbe.org/8exf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8exf RCSB], [https://www.ebi.ac.uk/pdbsum/8exf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8exf ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/TET5A_HUMAN TET5A_HUMAN] Osteogenesis imperfecta type 3. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TET5A_HUMAN TET5A_HUMAN] Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation (PubMed:33882302). Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs (By similarity).[UniProtKB:D3Z5S8]<ref>PMID:33882302</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu S]] | ||
| + | [[Category: Zhang X]] | ||
Revision as of 09:52, 15 March 2023
Crystal structure of human FAM46A-BCCIPa complex at 3.2 angstrom resolution
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