8b8o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:04, 18 October 2023) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8b8o is ON HOLD until Paper Publication
+
==Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide==
-
 
+
<StructureSection load='8b8o' size='340' side='right'caption='[[8b8o]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
Authors: Stewart, B.Z., Kvansakul, M.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8b8o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_papillomavirus_66 Human papillomavirus 66]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B8O FirstGlance]. <br>
-
Description: Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
[[Category: Kvansakul, M]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b8o OCA], [https://pdbe.org/8b8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b8o RCSB], [https://www.ebi.ac.uk/pdbsum/8b8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b8o ProSAT]</span></td></tr>
-
[[Category: Stewart, B.Z]]
+
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/SCRIB_HUMAN SCRIB_HUMAN] The disease is caused by mutations affecting the gene represented in this entry.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SCRIB_HUMAN SCRIB_HUMAN] Scaffold protein involved in different aspects of polarized cells differentiation regulating epithelial and neuronal morphogenesis. Most probably functions in the establishment of apico-basal cell polarity. May function in cell proliferation regulating progression from G1 to S phase and as a positive regulator of apoptosis for instance during acinar morphogenesis of the mammary epithelium. May also function in cell migration and adhesion and hence regulate cell invasion through MAPK signaling. May play a role in exocytosis and in the targeting synaptic vesicles to synapses. Functions as an activator of Rac GTPase activity.<ref>PMID:15182672</ref> <ref>PMID:15775968</ref> <ref>PMID:16344308</ref> <ref>PMID:16965391</ref> <ref>PMID:18641685</ref> <ref>PMID:18716323</ref> <ref>PMID:19041750</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Human papillomavirus 66]]
 +
[[Category: Large Structures]]
 +
[[Category: Kvansakul M]]
 +
[[Category: Stewart BZ]]

Current revision

Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide

PDB ID 8b8o

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8b8o"
Personal tools