Glyoxylate cycle
From Proteopedia
(Difference between revisions)
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The glyoxylate cycle uses six of the eight enzymes associated with the tricarboxylic acid cycle: citrate synthase, aconitase, succinate dehydrogenase, fumarase, and malate dehydrogenase. | The glyoxylate cycle uses six of the eight enzymes associated with the tricarboxylic acid cycle: citrate synthase, aconitase, succinate dehydrogenase, fumarase, and malate dehydrogenase. | ||
| - | + | [[Citrate Synthase]] | |
4C <scene name='43/430893/Cv/3'>oxaloacetate</scene> to a 6C molecule <scene name='43/430893/Cv/4'>citrate</scene> | 4C <scene name='43/430893/Cv/3'>oxaloacetate</scene> to a 6C molecule <scene name='43/430893/Cv/4'>citrate</scene> | ||
| - | + | [[Aconitase]] | |
6C Citrate => 6C <scene name='43/430893/Cv/5'>cis-Aconitate</scene> | 6C Citrate => 6C <scene name='43/430893/Cv/5'>cis-Aconitate</scene> | ||
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6C ''cis''-Aconitate => 6C <scene name='43/430893/Cv/6'>Isocitrate</scene> | 6C ''cis''-Aconitate => 6C <scene name='43/430893/Cv/6'>Isocitrate</scene> | ||
| - | + | [[Succinate Dehydrogenase]] | |
<scene name='43/430893/Cv/10'>Succinate</scene> => <scene name='43/430893/Cv/11'>Fumarate</scene> | <scene name='43/430893/Cv/10'>Succinate</scene> => <scene name='43/430893/Cv/11'>Fumarate</scene> | ||
| + | [[Fumarase]] | ||
| + | Fumarate => <scene name='43/430893/Cv/12'>L-Malate</scene> | ||
| - | The two cycles differ in that in the glyoxylate cycle, isocitrate is converted into <scene name='93/939250/Cv/1'>glyoxylate</scene> and | + | [[Malate dehydrogenase]] |
| + | *Step 9 = [[Krebs cycle step 8]] | ||
| + | L-Malate => <scene name='43/430893/Cv/3'>oxaloacetate</scene> | ||
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| + | The two cycles differ in that in the glyoxylate cycle, <scene name='43/430893/Cv/6'>isocitrate</scene> is converted into <scene name='93/939250/Cv/1'>glyoxylate</scene> and <scene name='43/430893/Cv/10'>Succinate</scene> by isocitrate lyase (ICL) instead of into α-ketoglutarate. | ||
*[[Malate synthase]] | *[[Malate synthase]] | ||
Revision as of 13:01, 28 November 2022
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