From Proteopedia
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| - | | + | #REDIRECT [[8owo]] This PDB entry is obsolete and replaced by 8owo |
| - | ==SMYD3 in complex with fragment FL01507==
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| - | <StructureSection load='7qa6' size='340' side='right'caption='[[7qa6]], [[Resolution|resolution]] 1.80Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[7qa6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QA6 FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9W9:3-oxidanylbenzenecarbonitrile'>9W9</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qa6 OCA], [https://pdbe.org/7qa6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qa6 RCSB], [https://www.ebi.ac.uk/pdbsum/7qa6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qa6 ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [https://www.uniprot.org/uniprot/SMYD3_HUMAN SMYD3_HUMAN] Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.<ref>PMID:15235609</ref> <ref>PMID:22419068</ref>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Homo sapiens]]
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| - | [[Category: Large Structures]]
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| - | [[Category: Cederfelt D]]
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| - | [[Category: Dobritzsch D]]
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| - | [[Category: Lund BA]]
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Current revision
- REDIRECT 8owo This PDB entry is obsolete and replaced by 8owo
