1j6z

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[[Image:1j6z.gif|left|200px]]
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{{Seed}}
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[[Image:1j6z.png|left|200px]]
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{{STRUCTURE_1j6z| PDB=1j6z | SCENE= }}
{{STRUCTURE_1j6z| PDB=1j6z | SCENE= }}
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'''UNCOMPLEXED ACTIN'''
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===UNCOMPLEXED ACTIN===
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==Overview==
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The dynamics and polarity of actin filaments are controlled by a conformational change coupled to the hydrolysis of adenosine 5'-triphosphate (ATP) by a mechanism that remains to be elucidated. Actin modified to block polymerization was crystallized in the adenosine 5'-diphosphate (ADP) state, and the structure was solved to 1.54 angstrom resolution. Compared with previous ATP-actin structures from complexes with deoxyribonuclease I, profilin, and gelsolin, monomeric ADP-actin is characterized by a marked conformational change in subdomain 2. The successful crystallization of monomeric actin opens the way to future structure determinations of actin complexes with actin-binding proteins such as myosin.
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The line below this paragraph, {{ABSTRACT_PUBMED_11474115}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11474115 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11474115}}
==About this Structure==
==About this Structure==
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[[Category: Adp-state]]
[[Category: Adp-state]]
[[Category: Tetramethylrhodamine-5-maleimide]]
[[Category: Tetramethylrhodamine-5-maleimide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:51:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 14:33:51 2008''

Revision as of 11:33, 1 July 2008

Image:1j6z.png

Template:STRUCTURE 1j6z

UNCOMPLEXED ACTIN

Template:ABSTRACT PUBMED 11474115

About this Structure

1J6Z is a Single protein structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

The crystal structure of uncomplexed actin in the ADP state., Otterbein LR, Graceffa P, Dominguez R, Science. 2001 Jul 27;293(5530):708-11. PMID:11474115

Page seeded by OCA on Tue Jul 1 14:33:51 2008

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