7w7g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:46, 30 October 2024) (edit) (undo)
 
Line 4: Line 4:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7w7g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W7G FirstGlance]. <br>
<table><tr><td colspan='2'>[[7w7g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W7G FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w7g OCA], [https://pdbe.org/7w7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w7g RCSB], [https://www.ebi.ac.uk/pdbsum/7w7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w7g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w7g OCA], [https://pdbe.org/7w7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w7g RCSB], [https://www.ebi.ac.uk/pdbsum/7w7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w7g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[https://www.uniprot.org/uniprot/UNC80_MOUSE UNC80_MOUSE] Auxiliary subunit of the NALCN sodium channel complex (PubMed:32620897, PubMed:19092807, PubMed:21040849). The NALCN sodium channel complex is a voltage-gated ion channel responsible for the resting Na(+) permeability that controls neuronal excitability (PubMed:32620897). This complex is activated by neuropeptides substance P, neurotensin. In addition, the channel is inhibited by extracellular Ca(2+) through the Ca(2+)-sensing receptor. UNC80 is essential for NALCN sensitivity to extracellular calcium.<ref>PMID:19092807</ref> <ref>PMID:21040849</ref> <ref>PMID:32620897</ref>
+
[https://www.uniprot.org/uniprot/E5CYJ9_MOUSE E5CYJ9_MOUSE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Current revision

Structure of Mammalian NALCN-FAM155A-UNC79-UNC80 quanternary complex

PDB ID 7w7g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7w7g"
Personal tools