Sandbox Reserved 1759
From Proteopedia
(Difference between revisions)
| Line 14: | Line 14: | ||
Ligand OLA is hydrogen bonded to <scene name='93/934003/Arg128_bonded_to_ola/1'>Arg128</scene>. OLA is also hydrogen bonded to a water molecule which is hydrogen bonded to Arg128. | Ligand OLA is hydrogen bonded to <scene name='93/934003/Arg128_bonded_to_ola/1'>Arg128</scene>. OLA is also hydrogen bonded to a water molecule which is hydrogen bonded to Arg128. | ||
== Structural highlights == | == Structural highlights == | ||
| - | The Protein is composed of alpha helix, beta sheet, and other structures. The protein consists of two major domains. The first domain contains 9 alpha helix and 15 beta sheets. The second domain contains 9 alpha helix and 15 beta sheets. In the first domain, the amino acid Arg148 that hydrogen bonds to the OLA ligand is contained within a beta sheet. | + | The Protein is composed of alpha helix, beta sheet, and other structures. When the alpha and beta structures are The protein consists of two major domains with what appears to be a 60% alpha and 40% beta in a <scene name='93/934003/60_alpha_and_40_beta/1'>cartoon view</scene>. The first domain contains 9 alpha helix and 15 beta sheets. The second domain contains 9 alpha helix and 15 beta sheets. In the first domain, the amino acid Arg148 that hydrogen bonds to the OLA ligand is contained within a beta sheet. |
| + | |||
| + | 40 beta 60 alpha | ||
<scene name='93/934003/Space_filling/1'>Space filling</scene> | <scene name='93/934003/Space_filling/1'>Space filling</scene> | ||
Revision as of 23:04, 9 December 2022
Mevalonate 3,5-Bisphosphate Decarboxylase Structure
| |||||||||||
References
- ↑ Azami Y, Hattori A, Nishimura H, Kawaide H, Yoshimura T, Hemmi H. (R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum. J Biol Chem. 2014 Jun 6;289(23):15957-67. doi: 10.1074/jbc.M114.562686. Epub 2014, Apr 22. PMID:24755225 doi:http://dx.doi.org/10.1074/jbc.M114.562686
