8bv8

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Current revision (09:59, 20 December 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8bv8 is ON HOLD until Paper Publication
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==Crystal structure of the phage Mu protein Mom inactive mutant S124A==
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<StructureSection load='8bv8' size='340' side='right'caption='[[8bv8]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8bv8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_Mu Escherichia phage Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BV8 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bv8 OCA], [https://pdbe.org/8bv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bv8 RCSB], [https://www.ebi.ac.uk/pdbsum/8bv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bv8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MOM_BPMU MOM_BPMU] Iron-binding protein that performs methylcarbamoylation of adenine using acetyl CoA (PubMed:32369169). This chemical modificaltion makes the viral DNA resistant to a variety of host type I and type II restriction enzymes by modifying approximately 15% of DNA adenine residues (PubMed:32369169). The modification called momylation changes adenine for N6-methylcarbamoyl adenine and occurs just before packaging (PubMed:1258376, PubMed:32369169). Target sequences are 5'-(C or G)-A-(Cor G)-N-(C or T)-3' (PubMed:1258376). Also usually modifies adenine residues in the host cellular DNA (PubMed:1258376).<ref>PMID:1258376</ref> <ref>PMID:32369169</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia phage Mu]]
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[[Category: Large Structures]]
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[[Category: Bochtler M]]
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[[Category: Guan C]]
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[[Category: Lee YJ]]
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[[Category: Lund SR]]
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[[Category: Raleigh EA]]
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[[Category: Silva RMB]]
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[[Category: Skowronek K]]
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[[Category: Slyvka A]]
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[[Category: Weigele PR]]

Current revision

Crystal structure of the phage Mu protein Mom inactive mutant S124A

PDB ID 8bv8

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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