This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1jgg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1jgg.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1jgg.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1jgg| PDB=1jgg | SCENE= }}
{{STRUCTURE_1jgg| PDB=1jgg | SCENE= }}
-
'''Even-skipped Homeodomain Complexed to AT-rich DNA'''
+
===Even-skipped Homeodomain Complexed to AT-rich DNA===
-
==Overview==
+
<!--
-
even-skipped is a homeobox gene important in controlling segment patterning in the embryonic fruit fly. Its homeobox encodes a DNA binding domain which binds with similar affinities to two DNA consensus sequences, one AT-rich, the other GC-rich. We describe a crystallographic analysis of the Even-skipped homeodomain complexed to an AT-rich oligonucleotide at 2.0 A resolution. The structure reveals a novel arrangement of two homeodomains bound to one 10 bp DNA sequence in a tandem fashion. This arrangement suggests a mechanism for the homeoproteins' regulatory specificity. In addition, the functionally important residue Gln50 is observed in multiple conformations making direct and water-mediated hydrogen bonds with the DNA bases.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8557047}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8557047 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8557047}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Homeodomain]]
[[Category: Homeodomain]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:11:37 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:12:28 2008''

Revision as of 17:12, 1 July 2008

Image:1jgg.png

Template:STRUCTURE 1jgg

Even-skipped Homeodomain Complexed to AT-rich DNA

Template:ABSTRACT PUBMED 8557047

About this Structure

1JGG is a Single protein structure of sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity., Hirsch JA, Aggarwal AK, EMBO J. 1995 Dec 15;14(24):6280-91. PMID:8557047

Page seeded by OCA on Tue Jul 1 20:12:28 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jgg"
Personal tools