1jgo

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[[Image:1jgo.gif|left|200px]]
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{{Seed}}
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[[Image:1jgo.png|left|200px]]
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{{STRUCTURE_1jgo| PDB=1jgo | SCENE= }}
{{STRUCTURE_1jgo| PDB=1jgo | SCENE= }}
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'''The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY'''
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===The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY===
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==Overview==
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Using X-ray crystallography, we have directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 A resolution. About 30 nucleotides of the mRNA are wrapped in a groove that encircles the neck of the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft between the head and the back of the platform. At the interface, only about eight nucleotides (-1 to +7), centered on the junction between the A and P codons, are exposed, and bond almost exclusively to 16S rRNA. The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting.
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The line below this paragraph, {{ABSTRACT_PUBMED_11511350}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11511350 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11511350}}
==About this Structure==
==About this Structure==
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[[Category: Protein synthesis]]
[[Category: Protein synthesis]]
[[Category: Ribosome assembly]]
[[Category: Ribosome assembly]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:12:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:13:05 2008''

Revision as of 17:13, 1 July 2008

Template:STRUCTURE 1jgo

The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY

Template:ABSTRACT PUBMED 11511350

About this Structure

1JGO is a Protein complex structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

The path of messenger RNA through the ribosome., Yusupova GZ, Yusupov MM, Cate JH, Noller HF, Cell. 2001 Jul 27;106(2):233-41. PMID:11511350

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