7qcn

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'''Unreleased structure'''
 
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The entry 7qcn is ON HOLD until 2024-02-24
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==Structure of the MUCIN-2 Cterminal domains: vWCN to TIL domains with a C2 symmetry==
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<StructureSection load='7qcn' size='340' side='right'caption='[[7qcn]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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Authors: Gallego, P., Hansson, G.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7qcn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QCN FirstGlance]. <br>
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Description: Structure of the MUCIN-2 Cterminal domains: vWCN to TIL domains with a C2 symmetry
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qcn OCA], [https://pdbe.org/7qcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qcn RCSB], [https://www.ebi.ac.uk/pdbsum/7qcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qcn ProSAT]</span></td></tr>
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[[Category: Gallego, P]]
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</table>
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[[Category: Hansson, G.C]]
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== Function ==
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[https://www.uniprot.org/uniprot/MUC2_HUMAN MUC2_HUMAN] Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.<ref>PMID:19432394</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Gallego P]]
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[[Category: Hansson GC]]

Revision as of 07:26, 8 March 2023

Structure of the MUCIN-2 Cterminal domains: vWCN to TIL domains with a C2 symmetry

PDB ID 7qcn

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