8ava

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'''Unreleased structure'''
 
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The entry 8ava is ON HOLD until Paper Publication
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==Leukotriene A4 hydrolase in complex with 4-(4-benzylphenyl)-oxazol-2-amine==
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<StructureSection load='8ava' size='340' side='right'caption='[[8ava]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ava]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AVA FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=OVO:4-[4-(phenylmethyl)phenyl]-1,3-oxazol-2-amine'>OVO</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ava FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ava OCA], [https://pdbe.org/8ava PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ava RCSB], [https://www.ebi.ac.uk/pdbsum/8ava PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ava ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LKHA4_HUMAN LKHA4_HUMAN] Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:1975494</ref> <ref>PMID:2244921</ref> <ref>PMID:12207002</ref> <ref>PMID:11917124</ref> <ref>PMID:15078870</ref> <ref>PMID:18804029</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Haeggstrom JZ]]
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[[Category: Teder T]]

Revision as of 07:28, 3 May 2023

Leukotriene A4 hydrolase in complex with 4-(4-benzylphenyl)-oxazol-2-amine

PDB ID 8ava

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