8h68
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II)== | |
| - | + | <StructureSection load='8h68' size='340' side='right'caption='[[8h68]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8h68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8H68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8H68 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PRD_900010:alpha-maltotetraose'>PRD_900010</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8h68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8h68 OCA], [https://pdbe.org/8h68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8h68 RCSB], [https://www.ebi.ac.uk/pdbsum/8h68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8h68 ProSAT]</span></td></tr> |
| - | [[Category: Ding | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/MALE_ECO57 MALE_ECO57] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides (By similarity).[https://www.uniprot.org/uniprot/NMAD1_CAEEL NMAD1_CAEEL] Dioxygenase that specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA (PubMed:25936839). N(6)-methyladenosine (m6A) DNA is involved in epigenetic transgenerational inheritance (PubMed:25936839). Plays an essential role in DNA replication and repair in the germline during meiosis (PubMed:31283754). Binds to components of the DNA replication machinery such as top-2, and directs their localization to DNA to control DNA replication (PubMed:31283754).<ref>PMID:25936839</ref> <ref>PMID:31283754</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Caenorhabditis elegans]] | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ding J]] | ||
| + | [[Category: Shi Y]] | ||
| + | [[Category: Yang H]] | ||
Revision as of 12:48, 22 February 2023
Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II)
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