8hqc

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'''Unreleased structure'''
 
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The entry 8hqc is ON HOLD until Paper Publication
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==Structure of a GPCR-G protein in complex with a natural peptide agonist==
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<StructureSection load='8hqc' size='340' side='right'caption='[[8hqc]], [[Resolution|resolution]] 3.89&Aring;' scene=''>
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Authors: Saha, S., Maharana, J., Yadav, M.K., Sarma, P., Chami, M., Banerjee, R., Shukla, A.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8hqc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HQC FirstGlance]. <br>
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Description: Structure of a GPCR-G protein in complex with a natural peptide agonist
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.89&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hqc OCA], [https://pdbe.org/8hqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hqc RCSB], [https://www.ebi.ac.uk/pdbsum/8hqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hqc ProSAT]</span></td></tr>
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[[Category: Shukla, A.K]]
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</table>
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[[Category: Saha, S]]
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== Function ==
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[[Category: Chami, M]]
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[https://www.uniprot.org/uniprot/C5AR1_MOUSE C5AR1_MOUSE] Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB:P21730]
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[[Category: Yadav, M.K]]
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__TOC__
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[[Category: Sarma, P]]
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</StructureSection>
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[[Category: Maharana, J]]
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[[Category: Homo sapiens]]
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[[Category: Banerjee, R]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Banerjee R]]
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[[Category: Chami M]]
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[[Category: Maharana J]]
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[[Category: Saha S]]
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[[Category: Sarma P]]
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[[Category: Shukla AK]]
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[[Category: Yadav MK]]

Revision as of 14:08, 18 October 2023

Structure of a GPCR-G protein in complex with a natural peptide agonist

PDB ID 8hqc

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