1ji8

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[[Image:1ji8.gif|left|200px]]
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{{STRUCTURE_1ji8| PDB=1ji8 | SCENE= }}
{{STRUCTURE_1ji8| PDB=1ji8 | SCENE= }}
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'''Solution Structure of Pyrobaculum Aerophilum DsrC/gamma subunit of dissimilatory sulfite reductase'''
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===Solution Structure of Pyrobaculum Aerophilum DsrC/gamma subunit of dissimilatory sulfite reductase===
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==Overview==
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The solution structure of DsrC, an archaeal homologue of the gamma subunit of dissimilatory sulfite reductase, has been determined by NMR spectroscopy. This 12.7-kDa protein from the hyperthermophilic archaeon Pyrobaculum aerophilum adopts a novel fold consisting of an orthogonal helical bundle with a beta hairpin along one side. A portion of the structure resembles the helix-turn-helix DNA-binding motif common in transcriptional regulator proteins. The protein contains two disulfide bonds but remains folded following reduction of the disulfides. DsrC proteins from organisms other than Pyrobaculum species do not contain these disulfide bonds. A conserved cysteine next to the C-terminus, which is not involved in the disulfide bonds, is located on a seven-residue C-terminal arm that is not part of the globular protein and is likely to dynamically sample more than one conformation.
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(as it appears on PubMed at http://www.pubmed.gov), where 11722571 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11722571}}
==About this Structure==
==About this Structure==
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1JI8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JI8 OCA].
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1JI8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JI8 OCA].
==Reference==
==Reference==
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[[Category: Psi]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:15:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:17:11 2008''

Revision as of 17:17, 1 July 2008

Image:1ji8.png

Template:STRUCTURE 1ji8

Solution Structure of Pyrobaculum Aerophilum DsrC/gamma subunit of dissimilatory sulfite reductase

Template:ABSTRACT PUBMED 11722571

About this Structure

1JI8 is a Single protein structure of sequence from Pyrobaculum aerophilum. Full experimental information is available from OCA.

Reference

Solution structure of Pyrobaculum aerophilum DsrC, an archaeal homologue of the gamma subunit of dissimilatory sulfite reductase., Cort JR, Mariappan SV, Kim CY, Park MS, Peat TS, Waldo GS, Terwilliger TC, Kennedy MA, Eur J Biochem. 2001 Nov;268(22):5842-50. PMID:11722571

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