8bxy

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'''Unreleased structure'''
 
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The entry 8bxy is ON HOLD until Paper Publication
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==FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group==
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<StructureSection load='8bxy' size='340' side='right'caption='[[8bxy]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8bxy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BXY FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bxy OCA], [https://pdbe.org/8bxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bxy RCSB], [https://www.ebi.ac.uk/pdbsum/8bxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bxy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Bouckaert J]]
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[[Category: Bridot C]]
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[[Category: Krammer E-M]]

Revision as of 20:30, 12 April 2023

FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group

PDB ID 8bxy

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