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1jjw

From Proteopedia

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[[Image:1jjw.gif|left|200px]]
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{{STRUCTURE_1jjw| PDB=1jjw | SCENE= }}
{{STRUCTURE_1jjw| PDB=1jjw | SCENE= }}
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'''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution'''
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===Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution===
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==Overview==
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The structure of the Haemophilus influenzae HslV protease of the HslUV 'prokaryotic proteasome' has been solved by molecular replacement and refined with data to 1.9 A resolution. The protease is a 'double donut' of hexameric rings; two alternative sets of intermolecular interactions between protomers in the rings result in 'quasi-equivalent' packing within the assembly. Anomalous scattering data from crystals with potassium present in the mother liquor reveal a K(+) ion bound with octahedral coordination near the active-site Thr1 residue. The site also binds Na(+) ions and is likely to bind Mg(2+), suggesting that monovalent and divalent metal ions may influence the catalytic activity of the protease.
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(as it appears on PubMed at http://www.pubmed.gov), where 11717526 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11717526}}
==About this Structure==
==About this Structure==
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[[Category: K anomalous scattering]]
[[Category: K anomalous scattering]]
[[Category: Quasi-equivalent packing]]
[[Category: Quasi-equivalent packing]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:18:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:21:25 2008''

Revision as of 17:21, 1 July 2008

Image:1jjw.png

Template:STRUCTURE 1jjw

Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution

Template:ABSTRACT PUBMED 11717526

About this Structure

1JJW is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:11717526

Page seeded by OCA on Tue Jul 1 20:21:25 2008

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