This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1jjx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1jjx.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1jjx.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1jjx| PDB=1jjx | SCENE= }}
{{STRUCTURE_1jjx| PDB=1jjx | SCENE= }}
-
'''Solution Structure of Recombinant Human Brain-type Fatty acid Binding Protein'''
+
===Solution Structure of Recombinant Human Brain-type Fatty acid Binding Protein===
-
==Overview==
+
<!--
-
Human brain-type fatty acid-binding protein (B-FABP) has been recombinantly expressed in Escherichia coli both unlabelled and 15N-enriched for structure investigation in solution using high-resolution NMR spectroscopy. The sequential assignments of the 1H and 15N resonances were achieved by applying multidimensional homo- and heteronuclear NMR experiments. The ensemble of the 20 final energy-minimized structures, representing human B-FABP in solution, have been calculated based on a total of 2490 meaningful distance constraints. The overall B-FABP structure exhibits the typical backbone conformation described for other members of the FABP family, consisting often antiparallel beta-strands (betaA to betaJ) that form two almost orthogonal beta-sheets, a helix-turn-helix motif that closes the beta-barrel on one side, and a short N-terminal helical loop. A comparison with the crystal structure of the same protein complexed with docosahexaenoic acid reveals only minor differences in both secondary structure and overall topology. Moreover, the NMR data indicate a close structural relationship between human B-FABP and heart-type FABP with respect to fatty acid binding inside the protein cavity.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12479569}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12479569 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12479569}}
==About this Structure==
==About this Structure==
-
1JJX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJX OCA].
+
1JJX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJX OCA].
==Reference==
==Reference==
Line 32: Line 36:
[[Category: Lipid binding protein]]
[[Category: Lipid binding protein]]
[[Category: Nmr spectroscopy]]
[[Category: Nmr spectroscopy]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:18:49 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:21:33 2008''

Revision as of 17:21, 1 July 2008

Image:1jjx.png

Template:STRUCTURE 1jjx

Solution Structure of Recombinant Human Brain-type Fatty acid Binding Protein

Template:ABSTRACT PUBMED 12479569

About this Structure

1JJX is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Solution structure of fatty acid-binding protein from human brain., Rademacher M, Zimmerman AW, Ruterjans H, Veerkamp JH, Lucke C, Mol Cell Biochem. 2002 Oct;239(1-2):61-8. PMID:12479569

Page seeded by OCA on Tue Jul 1 20:21:33 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jjx"
Personal tools