7trs

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'''Unreleased structure'''
 
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The entry 7trs is ON HOLD until 2024-08-02
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==Human M4 muscarinic acetylcholine receptor complex with Gi1 and the endogenous agonist acetylcholine==
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<StructureSection load='7trs' size='340' side='right'caption='[[7trs]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7trs]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TRS FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7trs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7trs OCA], [https://pdbe.org/7trs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7trs RCSB], [https://www.ebi.ac.uk/pdbsum/7trs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7trs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Belousoff MJ]]
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[[Category: Danev R]]
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[[Category: Glukhova A]]
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[[Category: Mobbs JI]]
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[[Category: Sexton PM]]
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[[Category: Thal DM]]
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[[Category: Vuckovic Z]]

Revision as of 06:55, 18 May 2023

Human M4 muscarinic acetylcholine receptor complex with Gi1 and the endogenous agonist acetylcholine

PDB ID 7trs

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