8c6i

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== Function ==
== Function ==
[https://www.uniprot.org/uniprot/CEIP2_HUMAN CEIP2_HUMAN] Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).[UniProtKB:A3KPQ7]<ref>PMID:28246172</ref>
[https://www.uniprot.org/uniprot/CEIP2_HUMAN CEIP2_HUMAN] Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).[UniProtKB:A3KPQ7]<ref>PMID:28246172</ref>
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==See Also==
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*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
== References ==
== References ==
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Revision as of 05:48, 7 June 2023

TMEM2 ectodomain

PDB ID 8c6i

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